Offered by the Department of Psychiatry at Beth Israel Deaconess Medical Center, a teaching hospital of Harvard Medical School.

Cognitive-Behavioral Therapy:
Clinical State of the Art

Michelle Friedman-Yakoobian, PhD, Robert M. Goisman, MD, and Matcheri S. Keshavan, MD

July 25 – 29, 2022 • Monday – Friday
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CBT is indicated as primary or adjunctive treatment for a wide range of mood, anxiety, and psychotic disorders. Simultaneously, cognitive impairments are increasingly being viewed as core disturbances in several neuropsychiatric disorders and are benefited by a cognitive approach such as cognitive remediation.

Topics in this course will include: a brief review of the development of behavioral and cognitive treatments as well as an overview of newer, third-wave behavioral treatments such as mindfulness and Acceptance and Commitment Therapy (ACT); practical applications of CBT and related treatments for anxiety disorders including panic, phobias, obsessive-compulsive disorder, and post-traumatic stress disorder; mood disorders; principles underlying the development of cognitive remediation for schizophrenia, mood disorders, ADHD, mild cognitive impairments, and autism; social skills training and cognitive restructuring for psychotic disorders; and the relationship of CBT to psychodynamic psychotherapy. We will also review efficacy data and therapeutic mechanisms for cognitive remediation approaches and discuss cognitive therapy approaches for bipolar disorder and for the treatment of delusions, hallucinations, and negative symptoms of schizophrenia. We will in part utilize a case presentation format, in which a case illustrating the subject matter of that morning will be presented and then discussed using the principles just developed. Live role-playing exercises will also be used to illustrate the application of skills. Participants will be invited to present their own cases for consultation.

Upon completion of this activity, participants will be able to:

  • Use specific techniques for improving functioning and reducing impact of anxiety in patients with anxiety disorders;
  • Evaluate specific CBT and acceptance/ mindfulness based interventions used in panic disorder, obsessive-compulsive disorder, phobias, and PTSD;
  • Apply cognitive and behavioral therapy methods and acceptance and commitment therapy in the treatment of patients with unipolar depression and with bipolar disorder;
  • Review principles and approaches to cognitive behavior therapy for psychotic disorders;
  • Determine areas of convergence as well as divergence in the relationship between CBT, acceptance and commitment therapy, and psychodynamic psychotherapy;
  • Recognize cognitive deficits and impaired neuroplasticity in schizophrenia;
  • Apply approaches to cognitive remediation in schizophrenia;
  • Describe the cognitive model of anxiety and its relationship to treatment;
  • Explain similarities and differences in the cognitive-behavioral treatment of unipolar depression and bipolar disorder;
  • Define mindfulness and its use in the treatment of anxiety disorders.


Michelle Friedman-Yakoobian, PhD is an Assistant Professor of Psychology in the Department of Psychiatry, Harvard Medical School and Beth Israel Deaconess Medical Center. She is the Co-Founder and Director of Research and Development at the Center for Early Detection, Assessment and Response to Risk. Dr. Yakoobian has trained scores of graduate students, psychiatry residents, and mental health professionals in CBT. She speaks regionally, nationally, and internationally on CBT, Acceptance and Commitment Therapy (ACT) and cognitive remediation. She is co-author of the Cognitive Behavioral Therapy (CBT) and Guide for Case Managers.

Robert M. Goisman, MD is an Associate Professor of Psychiatry (part-time) at Harvard Medical School, Beth Israel Deaconess Medical Center and the former Director of Medical Student Education at Massachusetts Mental Health Center. His research interests have included behavioral therapy, anxiety disorders, and psychosocial rehabilitation in chronic mental illness. Dr. Goisman is a past recipient of the Elvin V. Semrad Award for Excellence in Teaching at the Massachusetts Mental Health Center. He is a past recipient of the “Outstanding Psychiatrist Award” from the Massachusetts Psychiatric Society for Public Sector Service. He is a Founding Fellow of the Academy of Cognitive Therapy, a Distinguished Life Fellow of the American Psychiatric Association, and a Fellow of the Association for Behavioral and Cognitive Therapies. In 2011 he received the Special Faculty Prize for Sustained Excellence in Teaching from Harvard Medical School.

Matcheri S. Keshavan, MD is Stanley Cobb Professor of Psychiatry, Harvard Medical School, and Chairman of Psychiatry at the Beth Israel Deacon Medical Center. Dr. Keshavan is a world class teacher and researcher in schizophrenia. He has authored over 650 peer-reviewed publications as well as having authored four books and 100 reviews/book chapters. He is editor of Schizophrenia Research and serves on the editorial board of many respected journals. 

Date and timeAgenda Item 
Monday, July 25
8:30am – 9:00amRegistration
9:00am – 10:15amCognitive Remediation 1: Principles.Matcheri Keshavan, MD
10:15am – 10:30pmMorning Break
10:30am – 12:15pmCognitive Remediation 2: Techniques and evidence for efficacy.Matcheri Keshavan, MD
Tuesday, July 26
9:00am – 10:15amMood Disorders 1: the cognitive triad of depression, schemas and automatic thoughts, behavioral approaches and other homework tasks, case presentation.Michelle Friedman-Yakoobian, PhD
10:15am – 10:30amMorning Break
10:30am – 12:15pmMood Disorders 2: Acceptance/mindfulness approaches for depression, tracking and examining unhelpful thoughts, collaborative empiricism and hypothesis-testing, other cognitive strategies, indications and limitations, applications to bipolar disorder.Michelle Friedman-Yakoobian, PhD
Wednesday, July 27
9:00am – 10:15amAnxiety Disorders 2: CBT and ACT approaches for treating anxiety, the relaxation response and mindfulness meditation, the principle of exposure, making anxiety hierarchies, case presentation.Michelle Friedman-Yakoobian, PhD
10:15am – 10:30amMorning Break
10:30am – 12:15pmAnxiety Disorders 3: Applications to phobias and obsessive-compulsive disorder, cognitive-behavioral treatment of panic attacks, drug and non-drug treatments, safety behaviors.Michelle Friedman-Yakoobian, PhD
Thursday July 28
9:00am – 10:15amPsychotic Disorders: CBT and Acceptance/mindfulness Approaches for Psychotic DisordersMichelle Friedman-Yakoobian, PhD
10:15am – 10:30amMorning Break
10:30am – 12:15pmAnxiety Disorders 1: approaches to post-traumatic stress disorder, exposure treatments in PTSD, stress inoculation.Michelle Friedman-Yakoobian, PhD
Friday, July 29
9:00am – 10:15amOverview of Course, Historical Development of CBTRobert M. Goisman, MD
10:15am – 10:30amMorning Break
10:30am – 12:15pmCommon Factors of Effective Psychotherapy: Convergence and divergence of CBT with psychodynamic psychotherapy, the “Y-Model”.Robert M. Goisman, MD